Adenohypophysial Dopamine Content during Physiological Changes in Prolactin Secretion*
نویسندگان
چکیده
منابع مشابه
Excitatory Neuromodulator Reduces Dopamine Release, Enhancing Prolactin Secretion
Hypothalamic dopamine neurons inhibit pituitary prolactin secretion. In this issue of Neuron, Lyons et al. provide evidence for a novel model, whereby the excitatory neuropeptide TRH depolarizes gap-junction-coupled dopamine neurons, leading to a shift in the population pattern of action potentials from phasic burst firing to regular tonic firing, hypothetically reducing dopamine release while ...
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Prolactin is unique among the anterior pituitary hormones in that it is under tonic inhibitory control by the hypothalamus. There is much evidence that the major prolactin inhibitory factor is dopamine [l-31. However, there are a number of physiological stimuli of prolactin secretion which can ‘override’ the effect of dopamine and one of the most important of these is oestrogen. Oestrogens are ...
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The effects were investigated, in 12 dogs, of the infusion of dopamine 10 or 30 micrograms kg-1 min-1 on circulating glucose, glycerol, lactate and potassium concentrations. Both doses of dopamine produced in initial increase in blood glucose concentration (P less than 0.05) followed by hypoglycaemia (P less than 0.05). Lipolysis was stimulated as shown by an increase in plasma glycerol concent...
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Prolactin plays major roles in maintaining the corpora lutea of pregnancy and in the synthesis of milk during lactation. The hypothalamic mechanisms involved in these functions have been investigated. Mating leads to a surge of prolactin and programs daily surges during early pregnancy. The expression of Fos-immunoreactivity shows that mating activates several hypothalamic nuclei, particularly ...
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Dopamine (DA) is known as a primary regulator of prolactin secretion (PRL) and angiotensin II (Ang II) has been recognized as one brain inhibitory factor of this secretion. In this work, estrogen-primed or unprimed ovariectomized rats were submitted to the microinjection of saline or Ang II after previous microinjection of saline or of DA antagonist (haloperidol, sulpiride or SCH) both in the m...
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ژورنال
عنوان ژورنال: Endocrinology
سال: 1984
ISSN: 0013-7227,1945-7170
DOI: 10.1210/endo-115-6-2091